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The San Diego Alzheimer's Disease Resource Center for Minority Aging Research (AD-RCMAR)
A partnership between UC San Diego and San Diego State University
DATA RESOURCES
Multiple data sources are available to AD-RCMAR Scientists and applicants, including:
Name of Dataset
Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Health and Retirement Study (HRS)
Rancho Bernardo Study of Healthy Aging (RBS)
Health and Aging Brain Study-Health Disparities (HABS-HD)
Hispanic – Established Populations for the Epidemiologic Study of the Elderly (H-EPESE)
Alzheimer’s Disease Cooperative Study (ADCS)
UCSD Shiley-Marcos ADRC Clinical Core Database
National Alzheimer’s Coordinating Center (NACC)
Successful Aging Evaluation (SAGE)
Study Aims
Multi-center epidemiologic study in Hispanic/Latino populations to assess role of acculturation in prevalence and development of disease and to identify factors affecting health.
Longitudinal study of U.S. adults aged 50+ designed to inform retirement research
Community-based cohort study of adults from the Rancho Bernardo suburb of San Diego, CA focused on cardiovascular disease, diabetes, bone disease, and cognitive function
The HABS-HD seeks to understand the biological, social and environmental factors that impact brain aging among diverse communities
Longitudinal study to provide estimates of physical health & mental health conditions, functional impairment and to compare to other populations
AD Clinical Trials addressing treatments for cognitive and behavioral symptoms
Multiple studies aiming to understand the causes, clinical features and treatments for MCI and ADRD
Facilitates collaborative research on ADRD
All of Us is building a diverse database that can inform thousands of studies on a variety of health conditions
Aims to investigate what factors (emotional, cognitive, genetic, social, physical, etc.) are associated with successful aging across the lifespan
To share measures of neighborhood disadvantage with the public, including educational institutions, health systems,
Population
16,415 diverse Hispanics/Latinos
~20,000, nationally representative
2,500 predominantly Northern European-American and middle to upper-middle class
1,000 Mexican-Americans, 1,000 non-Hispanic Whites, and 1,000 African-Americans from North Texas
3,050 Mexican-Americans aged 65+ years (8 waves of data) with an additional sample of 75+ years in wave 5.
6,500 people and 25,000 samples
Over 3,500 older adults, including 17% Latinos
35,000+ older adults
1,000,000 racially diverse people across the US
1,800 randomly selected, demographically representative, older adult residents of San Diego, CA
American Community Survey (ACS) 5-Year Data
Variables
Neurocognitive,sociocultural (e.g., acculturation), cardiometabolic (e.g., ECG), and multilayered –omics (e.g., whole genome sequences)
Multiple domains of health
Multiple domains of health and health status including cognitive, physical, sensory, and pulmonary function, biomarkers, and imaging.
Neurocognitive testing, neuroimaging, and biomarkers
Multiple domains of physical, mental health, cognition, functional status, sociodemographics
Biospecimens, brain imaging data, biochemical biomarkers, medications, MMSE, ADAS-cog, Clinical Dementia Rating Scale, Neuropsychiatric Inventory, CSF and serum data
Multiple variables, including MINT, arterial stiffness, caregiver stress, medical, neurological and neuropsychological data, MRI, CSF data and quantitative MR brain imaging
National standard clinical and neuropathological data (prospective and longitudinal) (Uniform Data Set, Neuropathology Data Set, Minimum Data Set)
EHR data, genomics, physical measurements and wearables, personal history, lifestyle, healthcare access and utilization, social determinants of health
Broad range of topics related to successful aging assessed by questionnaire, as well as genetic data
17 measures of social determinants of health across small,
population sensitive areas. It includes factors for the theoretical domains of income, education, employment, and housing quality.