Data | The San Diego Alzhei

Name of Dataset

Study Aims

Multi-center epidemiologic study in Hispanic/Latino populations to assess role of acculturation in prevalence and development of disease and to identify factors affecting health.

Longitudinal study of U.S. adults aged 50+ designed to inform retirement research

Community-based cohort study of adults from the Rancho Bernardo suburb of San Diego, CA focused on cardiovascular disease, diabetes, bone disease, and cognitive function

The HABS-HD seeks to understand the biological, social and environmental factors that impact brain aging among diverse communities

Longitudinal study to provide estimates of physical health & mental health conditions, functional impairment and to compare to other populations

AD Clinical Trials addressing treatments for cognitive and behavioral symptoms

Multiple studies aiming to understand the causes, clinical features and treatments for MCI and ADRD

Facilitates collaborative research on ADRD

All of Us is building a diverse database that can inform thousands of studies on a variety of health conditions

Aims to investigate what factors (emotional, cognitive, genetic, social, physical, etc.) are associated with successful aging across the lifespan

To share measures of neighborhood disadvantage with the public, including educational institutions, health systems,

Population

16,415 diverse Hispanics/Latinos

~20,000, nationally representative

2,500 predominantly Northern European-American and middle to upper-middle class

1,000 Mexican-Americans, 1,000 non-Hispanic Whites, and 1,000 African-Americans from North Texas

3,050 Mexican-Americans aged 65+ years (8 waves of data) with an additional sample of 75+ years in wave 5.

6,500 people and 25,000 samples

Over 3,500 older adults, including 17% Latinos

35,000+ older adults

1,000,000 racially diverse people across the US

1,800 randomly selected, demographically representative, older adult residents of San Diego, CA

American Community Survey (ACS) 5-Year Data

Variables

Neurocognitive,sociocultural (e.g., acculturation), cardiometabolic (e.g., ECG), and multilayered –omics (e.g., whole genome sequences)

Multiple domains of health

Multiple domains of health and health status including cognitive, physical, sensory, and pulmonary function, biomarkers, and imaging.

Neurocognitive testing, neuroimaging, and biomarkers

Multiple domains of physical, mental health, cognition, functional status, sociodemographics

Biospecimens, brain imaging data, biochemical biomarkers, medications, MMSE, ADAS-cog, Clinical Dementia Rating Scale, Neuropsychiatric Inventory, CSF and serum data

Multiple variables, including MINT, arterial stiffness, caregiver stress, medical, neurological and neuropsychological data, MRI, CSF data and quantitative MR brain imaging

National standard clinical and neuropathological data (prospective and longitudinal) (Uniform Data Set, Neuropathology Data Set, Minimum Data Set)

EHR data, genomics, physical measurements and wearables, personal history, lifestyle, healthcare access and utilization, social determinants of health

Broad range of topics related to successful aging assessed by questionnaire, as well as genetic data

17 measures of social determinants of health across small,
population sensitive areas. It includes factors for the theoretical domains of income, education, employment, and housing quality.

The San Diego Alzheimer's Disease Resource Center for Minority Aging Research (AD-RCMAR)

A partnership between UC San Diego and San Diego State University

DATA RESOURCES